兰天明,博士,教授/博士生导师,深圳市“梧桐凤凰”人才,农业农村部农业基因组学重点实验室副主任,国际生物多样性标准ISO-TC331工作组专家。2024年7月,高层次人才(成栋杰出人才)引进到东北林业大学从事科研与教学工作,搭建野生动物演化与保护多组学研究平台,担任课题组组长。
1. 研究方向
主要以基因组、转录组、蛋白组、代谢组、单细胞组和空间组等多维组学技术和手段,在各个尺度上揭示濒危物种的遗传结构、遗传多样性、遗传风险等,对濒危物种的遗传学表现和特征进行总结和归纳,探索和评估野生动物的濒危机制以及遗传拯救策略,提出物种保护新方法。并通过这些多组学手段去揭示野生动物对生存环境适应的遗传机制以及关键生物学特征的遗传基础等。同时,结合比较基因组学和古基因组学揭示动物的起源、演化、迁移等大时间尺度上的演化事件等。跨越时间和空间,总结过去、现在和未来,去试图理解和解释动物世界中普遍存在的生物学规律。近年来,在Nature, Nature Genetics, Nature Communications, PNAS, Protein & Cell, Science Bulletin, Molecular Ecology Resource, GigaScience, iScience等杂志发表研究论文30余篇,并获得多项软件著作权和发明专利。担任BMC Genomics杂志编委成员,Nucleic Acids Research, Journal of Advanced Research, iScience, Scientific data, Molecular Ecology Resources等杂志审稿人。
2. 工作经历
2024/07至今,东北林业大学,野生动物与自然保护地学院,教授/博士生导师
2013/07-2024/06,深圳华大生命科学研究院,助理研究员、副研究员/博士生导师、研究员/博士生导师
3. 教育经历
2018/01-2022/05,哥本哈根大学,生物信息学,博士
2010/09-2013/07,东北林业大学,生理学,硕士
2006/09-2010/07,东北林业大学,野生动物与自然保护区管理(动物科学),本科
4. 主要研究论文:第一和通讯(含共同)
1. Large-scale genome sequencing of giant pandas improves the understanding of population structure and future conservation initiatives. PNAS, 2024 (IF=9.4,Q1)
2. Genomic exploration of the endangered oriental stork, Ciconia boyciana, sheds light on migration adaptation and future conservation. GigaScience, 2024 (IF=11.8,Q1)
3. Haplotype-resolved chromosomescale genomes of the asian and african Savannah Elephants. Scientific Data, 2024 (IF=9.8,Q1)
4. A simple and effective method to enrich endogenous DNA from mammalian faeces. Molecular Ecology Resources, 2024 (IF=5.5,Q1)
5. Haplotype-resolved and chromosome-scale genomes provide insights into co-adaptation between the Amur tiger and Amur leopard. Zoological Research, 2023 (IF=4.9,Q1)
6. Single-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism. BMC Biology, 2023 (IF=5.4,Q1)
7. Distinct and shared endothermic strategies in the heat producing tissues of tuna and other teleosts. Science China-life Science, 2023 (IF=10.4,Q1)
8. Whole-genome resequencing of Chinese pangolins reveals a population structure and provides insights into their conservation. Communications Biology, 2022 (IF=6.5,Q1)
9. The chromosome-scale genome of the raccoon dog: Insights into its evolutionary characteristics. iScience, 2022 (IF=6.11,Q1)
10. Genomic consequences of inbreeding in the South China tiger: a comparative study with the Amur tiger. Molecular Ecology Resources, 2022 (IF=8.67,Q1)
11. Genomic investigation of the Chinese alligator reveals wild-extinct genetic diversity and genomic consequences of their continuous decline. Molecular Ecology Resources, 2022 (IF=8.67,Q1)
12. Chromosome-scale assembly and whole-genome sequencing of 266 giant panda roundworms provide insights into their evolution, adaptation and potential drug targets. Molecular Ecology Resources, 2022 (IF=8.67,Q1)
13. Single cell atlas for 11 non-model mammals, reptiles and birds. Nature Communications, 2021 (IF=17.69,Q1)
14. Chromosome-scale genomes provide new insights into subspecies divergence and evolutionary characteristics of the giant panda. Science Bulletin, 2021 (IF=20.58,Q1)
15. Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda. Protein & Cell, 2020 (IF=15.33,Q1)
16. An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole-genome sequencing data. Ecology and Evolution, 2020 (IF=3.17,Q2)
17. Improving Species Identification of Ancient Mammals Based on Next-Generation Sequencing Data. Genes (Basel), 2019 (IF=4.14,Q2)
18. Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia. Nature Genetics, 2018 (IF=41.31,Q1)
19. Deep whole-genome sequencing of 90 Han Chinese genomes. Gigascience, 2017 (IF=7.66,Q1)
20. 1000 Genomes Project Consortium. 2015. A global reference for human genetic variation. Nature, 2015 (IF=50.5,Q1)
5. 实验室招生
实验室每年招收硕士研究生2-3名,欢迎具有生命科学、生物信息学、基因组学、计算机科学和数学等背景的应届推免生咨询;欢迎统考生在正式报名前发送简历咨询。
联系邮箱:lantianming1314@126.com
地址:黑龙江省哈尔滨市和兴路26号,东北林业大学主楼西217室。
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