兰天明，博士，教授/博士生导师，全国林草创新科技青年拔尖人才，深圳市“梧桐凤凰”人才。担任农业农村部农业基因组学重点实验室副主任，国际生物多样性标准ISO-TC331工作组专家，第五届黑龙江省青年科技工作者协会委员，黑龙江省动物学会理事、副秘书长。在东北林业大学搭建了野生动物演化与保护多组学研究平台，担任课题组组长。同时，在野生动物与自然保护地学院担任野生动物与自然保护区管理专业负责人；野生动植物保护与利用（专业学位）学科带头人。
1. 研究方向
主要以基因组、转录组、蛋白组、代谢组、单细胞组和空间组等多维组学技术和手段，在各个尺度上揭示濒危动物的遗传表征，对生存环境适应的遗传机制以及关键生物学特征的遗传基础等，并对其进行总结和归纳，探索和评价野生动物的致濒机理和解濒策略，提出物种保护新方法。同时，课题组还通过比较基因组学和古基因组学揭示动物的起源、演化、迁移等大时间尺度上的演化事件，跨越时间和空间，总结过去、现在和未来，去试图理解和解释动物世界中普遍存在的生物学规律。近年来，在Nature, Nature Genetics, Nature Communications, PNAS, Protein & Cell, Science Bulletin, Molecular Biology and Evolution, Molecular Ecology Resource（5篇）, Journal of Genetics and Genomics, Communications Biology和BMC Biology等杂志发表研究论文30余篇，并获得多项软件著作权和发明专利的授权。担任Zoological Research和BMC Genomics杂志编委委员，GigaScience杂志青年编委委员，同时也是Nucleic Acids Research, Journal of Advanced Research, iScience, Scientific data, Molecular Ecology Resources等多个杂志的审稿人。
2. 工作经历
2024/07至今，东北林业大学，野生动物与自然保护地学院，教授/博士生导师
2013/07-2024/06，深圳华大生命科学研究院，助理研究员、副研究员/博士生导师、研究员/博士生导师
3. 教育经历
2018/01-2022/05，哥本哈根大学，生物信息学，博士
2010/09-2013/07，东北林业大学，生理学，硕士
2006/09-2010/07，东北林业大学，野生动物与自然保护区管理（动物科学），本科
4. 科研项目与学术成果
主要研究论文：第一和通讯（含共同）
1. Optimizing genome-wide detection of runs of homozygosity: impacts of reference genome quality and sequencing parameters on inbreeding assessment. Molecular Ecology Resources, 2026 (IF5y= 8.0，Q1，Top)
2. Population genomics reveals deep diversification in Malayan pangolins. Molecular Biology and Evolution, 2026 (IF5y= 11.9，Q1，Top)
3. Revealing extensive inbreeding and less-efficient purging of deleterious mutations in wild Amur tigers in China. Journal of Genetics and Genomics, 2025 (IF5y= 6.4，Q1，Top)
4. Enhancing inbreeding estimation and global conservation insights through chromosome-level assemblies of the Chinese and Malayan pangolin. GigaScience, 2025 (IF5y= 11.1，Q1)
5. Population genetics reveal potential threats from low maternal genetic diversity in wild Asian elephants in China. Global Ecology and Conservation, 2025 (IF5y= 4.1，Q1)
6. Mitochondrial genomes reveal low genetic diversity in snow leopards. Conservation Genetics, 2025 (IF5y=2.2，Q2)
7. Large-scale genome sequencing of giant pandas improves the understanding of population structure and future conservation initiatives. PNAS, 2024 (IF5y=10.6，Q1，Top)
8. A simple and effective method to enrich endogenous DNA from mammalian faeces. Molecular Ecology Resources, 2024 (IF5y= 8.0，Q1，Top)
9. Genomic exploration of the endangered oriental stork, Ciconia boyciana, sheds light on migration adaptation and future conservation. GigaScience, 2024 (IF5y=11.1，Q1)
10. Haplotype-resolved chromosome scale genomes of the asian and african Savannah Elephants. Scientific Data, 2024 (IF5y=8.7，Q1)
11. Haplotype-resolved and chromosome-scale genomes provide insights into co-adaptation between the Amur tiger and Amur leopard. Zoological Research, 2024 (IF5y=4.7，Q1，Top)
12. Single-nucleus transcriptome inventory of giant panda reveals cellular basis for fitness optimization under low metabolism. BMC Biology, 2023 (IF5y=5.4，Q1，Top)
13. Distinct and shared endothermic strategies in the heat producing tissues of tuna and other teleosts. Science China-life Science, 2023 (IF5y=8.1，Q1，Top)
14. Whole-genome resequencing of Chinese pangolins reveals a population structure and provides insights into their conservation. Communications Biology, 2022 (IF5y=5.8，Q1，Top)
15. The chromosome-scale genome of the raccoon dog: Insights into its evolutionary characteristics. iScience, 2022 (IF5y=5.0，Q1)
16. Genomic consequences of inbreeding in the South China tiger: a comparative study with the Amur tiger. Molecular Ecology Resources, 2022 (IF5y= 8.0，Q1，Top)
17. Genomic investigation of the Chinese alligator reveals wild-extinct genetic diversity and genomic consequences of their continuous decline. Molecular Ecology Resources, 2022 (IF5y= 8.0，Q1，Top)
18. Chromosome-scale assembly and whole-genome sequencing of 266 giant panda roundworms provide insights into their evolution, adaptation and potential drug targets. Molecular Ecology Resources, 2022 (IF5y= 8.0，Q1，Top)
19. Single cell atlas for 11 non-model mammals, reptiles and birds. Nature Communications, 2021 (IF5y=17.2，Q1，Top)
20. Chromosome-scale genomes provide new insights into subspecies divergence and evolutionary characteristics of the giant panda. Science Bulletin, 2021 (IF5y=17.6，Q1，Top)
21. Genomic and transcriptomic analysis unveils population evolution and development of pesticide resistance in fall armyworm Spodoptera frugiperda. Protein & Cell, 2020 (IF5y=19.5，Q1，Top)
22. An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole-genome sequencing data. Ecology and Evolution, 2020 (IF5y=2.8，Q2)
23. Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia. Nature Genetics, 2018 (IF5y=37.4，Q1，Top)
24. Deep whole-genome sequencing of 90 Han Chinese genomes. GigaScience, 2017 (IF5y=11.1，Q1)
25. 1000 Genomes Project Consortium. 2015. A global reference for human genetic variation. Nature, 2015 (IF5y=55，Q1，Top)
科研项目
1. 圈养东北虎群体中有害突变快速积累的驱动机制，国家自然科学基金面 上基金项目，主持
2. 大型濒危哺乳动物保护与演化基因组学研究，黑龙江省重点研发计划指导类项目，主持
3. 大规模食肉目动物进化基因组学研究，东北林业大学“成栋杰出青年”，主持
4. 基因组中有害突变对圈养东北虎野化放归的影响研究，中国博士后科学基金面上资助，主持
5. 联系方式
实验室每年招收3-5名硕士研究生，欢迎有生物学、基因组学、生物信息学、计算机科学、数学等背景的同学前来咨询。
联系方式：lantianming1314@126.com；lantianming@nefu.edu.cn
